12 August 2016
Brain Imaging Genetics: Genetics for Imagers
This intensive one-week course covers various aspects of genetics analyses of neuroimaging data. The course will start with basic information on the architecture of the human genome and the basis of heritability. We will then move on to the statistical analysis of single common genetic variant for the different imaging modalities (structural imaging based on (sub)cortical volumetry or diffusion tensor imaging and brain activity/functional connectivity based on (resting state) fMRI). This will be followed by analyses of whole gene and genome‐wide association studies and the meta-analysis of such data. Other important topics include the imputation of genetic data and linking genetics to behaviour via the brain – the essence of Cognomics research. We will conclude with approaches for the analysis of rare genetic variants.
The lecture programme will be supplemented with hands‐on computer exercises and demonstrations. Importantly, you will also learn how to genotype single nucleotide polymorphisms and score the genotypes in the wetlab. Evenings will be reserved for social activities.
Research school and faculty
The school is directed at national and international graduate students and junior postdocs (max. 40) who wish to develop their knowledge and skills on state‐of‐the‐art developments in the field of neuroimaging genetics. The faculty includes researchers involved in the largest imaging genetics consortium world‐wide – the ENIGMA Consortium – and the Dutch Cognomics Program.
Prof. Dr. B. (Barbara) Franke, Chair of the Nijmegen Cognomics Initiative
Donders Institute for Brain, Cognition and Behaviour
Radboud university medical centre
The summer school is designed for PhD candidates or junior postdocs; for some Master students it might also be possible to follow the course after a relevant internship.
After this course you are able to:
- Prepare genetics data for imaging genetics analyses
- Genotype single nucleotide polymorphisms and determine the quality of genotyping data
- Perform analyses combining imaging and genetics data
- Determine whether the effects of a gene on behaviour are mediated by brain phenotypes
EUR 450: The course fee includes the registration fee, course materials, access to library and IT facilities, coffee/tea, lunch, and a number of social activities.
10% discount for early bird applicants. The early bird deadline is 1 April 2016.
15% discount for students and PhD candidates from Radboud University and partner universities.
EUR 195: Housing (optional)